Intervenção Coronária Percutânea

NEWS • INTERVENTIONALTCT 2017

ORBITA: PCI Offers No Symptom Improvement Over Sham Procedure

The intriguing study, which hints at a placebo effect of PCI, left physicians debating the merits of revascularization in stable coronary artery disease.

DENVER, CO—Stable angina patients, even those with severe coronary stenosis, who undergo PCI for single-vessel disease fare no better than individuals who undergo a sham procedure when it comes to an improvement in exercise capacity and angina symptoms, according to the results of a new study presented here and published simultaneously in the Lancet.

On the last day of TCT 2017, the ORBITA study provided an intriguing twist to a meeting devoted to coronary revascularization, with investigators suggesting PCI is no better than a placebo when it comes to the improvement of symptoms in stable patients with single-vessel disease.

Lead investigator Rasha Al-Lamee, MBBS (Imperial College London, England), who presented the results during the late-breaking clinical trial session, cautioned against overinterpreting the findings. She pointed out that patients in ORBITA had good left ventricular function and single-vessel coronary artery disease easily treated by angioplasty.

To extrapolate those results to a higher-risk population would be a mistake, she said.

“I would say that this is the first placebo-controlled trial of angioplasty,” said Al-Lamee. “Of course, it’s something that’s interesting and will stimulate debate, and may even be used in guideline discussions, but the guidelines are based on thinking about the whole population.”

Para continuar lendo:
https://www.tctmd.com/news/orbita-pci-offers-no-symptom-improvement-over-sham-procedure

Fonte: TCTMD
Por By Michael O'Riordan